In vitro antibacterial activity of the peptide PsVP-10 against antimicrobial-resistant Enterococcus faecalis isolated from clinical samples
| datacite.alternateIdentifier.doi | https://doi.org/10.1093/jac/dkh067 | |
| datacite.alternateIdentifier.issn | 0305-7453 | |
| datacite.creator | Padilla, C. | |
| datacite.creator | Lobos, O. | |
| datacite.creator | Brevis, P. | |
| datacite.creator | Abaca, P. | |
| datacite.creator | Hubert, E. | |
| datacite.date.issued | 2004-02 | |
| datacite.subject | antibiotics; multiresistance and human infections | en |
| datacite.title | In vitro antibacterial activity of the peptide PsVP-10 against antimicrobial-resistant Enterococcus faecalis isolated from clinical samples | en |
| dc.date.accessioned | 2007-03-21T20:52:49Z | |
| dc.date.available | 2007-03-21T20:52:49Z | |
| dc.description | Padilla, C. (reprint author), 2 Norte 685, Talca, Chile.Univ Talca, Lab Invest Microbiol, Talca, Chile. | en |
| dc.description.abstract | Objective: To analyse the antimicrobial activity of the peptide PsVP-10 against 67 resistant Enterococcus faecalis strains isolated from clinical samples. Methods: The qualitative disc diffusion method and MIC determinations were used. Results: The presence of several multidrug-resistant phenotypes of E. faecalis was demonstrated, in which there were high MICs to chloramphenicol, tetracycline, vancomycin, cefaloridine, ampicillin and gentamicin. In comparison, the peptide PsVP-10 showed lower MICs against all the multidrug-resistant and susceptible E. faecalis. Conclusions: There is an urgent need for the development of novel antimicrobial agents against the highly resistant E. faecalis. The present study shows that the peptide PsVP-10 might make a contribution to the solution of this serious problem. | en |
| dc.format.extent | 2825 bytes | |
| dc.format.mimetype | text/html | |
| dc.identifier.citation | Journal of Antimicrobial Chemotherapy 53 (2): 390-392 | en |
| dc.identifier.uri | https://repositorio.utalca.cl/repositorio/handle/1950/3336 | |
| dc.language | en | |
| dc.publisher | Oxford University Press | en |
| oaire.resourceType | Artículo | en |
| utalca.index | Artículo de publicación ISI |
